YEJM MODULATES ACTIVITY OF THE YCIM/FTSH PROTEASE COMPLEX TO PREVENT LETHAL ACCUMULATION OF LIPOPOLYSACCHARIDE

YejM Modulates Activity of the YciM/FtsH Protease Complex To Prevent Lethal Accumulation of Lipopolysaccharide

ABSTRACT Lipopolysaccharide (LPS) is an essential glycolipid present in the outer membrane (OM) of many Gram-negative bacteria.Balanced biosynthesis of LPS is critical for cell viability; too little LPS weakens the OM, while too much LPS is lethal.In Escherichia coli, this balance is maintained by the YciM/FtsH protease complex, which adjusts LPS l

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Epoetin zeta in the management of anemia associated with chronic kidney disease, differential pharmacology and clinical utility

Mary Lynn Davis-Ajami,1 Jun Wu,2 Katherine Downton,3 Emilie Ludeman,3 Virginia Noxon4 1Organizational Systems and Adult Health, University of Maryland School of Nursing, Baltimore, MD, USA; 2South Carolina College of Pharmacy, University of South Carolina, Greenville, SC, USA; 3Health Sciences and Human Services Library, University of Maryland, Bal

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Microbial community shifts elicit inflammation in the caecal mucosa via the GPR41/43 signalling pathway during subacute ruminal acidosis

Abstract Background Dietary structure in ruminants is closely connected with the composition of gastrointestinal microbiota.Merging study has shown that dietary induced SARA causes the alteration of microbial 730 sunken lake road community in the cecum leading to the local inflammation.However, the mechanisms of cecum inflammation elicited by the s

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